Surprisingly strong, and came on very quickly. Killed my pain, along with any chance of thinking straight. ;-) Luckily, I didn't have to think at all, because music was deep and layer-full, and sound was kaleidoscopic during the peak. Smell and taste is sweet, mildly skunky, almost a slight hint of bergamot. Caution to pain patients: UP + PAIN FREE = Chance of getting too busy puttering around- don't cause yourself pain later!