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The Best Cannabis Strains for Pain

(Gillian Levine for Leafly)

One of the most common applications for medical cannabis is pain, whether it’s inflammation, headaches, neuropathic pain, muscle soreness, spinal injury, fibromyalgia, or cramps. Patients have seen varying degrees of success with cannabis in treating pain-related ailments, depending on the type of pain, the intensity, and the individual’s own physiology.

How Cannabis Relieves Different Types of Pain

This guide is informed both by user-submitted strain reviews and chemical profile data, as certain cannabinoids and terpenes are known to have areas of specialization such as pain. Because every person’s experience is so nuanced, we recommend sampling several of these suggestions and maybe even experiment with them in different forms, like topicals, oils, or even transdermal patches. Smoking and vaporizing are great ways to get the plant’s painkilling properties quickly, but read up on non-smoking consumption methods and cannabis concentrate alternatives to get an idea of the full spectrum of options available to you.

Cannabis Strains That Help With Generalized Pain

Leafly ACDC cannabis strain tileLeafly ACDC cannabis strain effects

Find ACDC Nearby

All hail ACDC, one of the most effective painkilling strains out there due to its one-two punch of cannabinoids CBD and THC. As a general rule, cannabis strains with high amounts of both THC and CBD tend to make the best pain medicines, and there are plenty of high-CBD strains out there offering similar chemical profiles as ACDC.

Leafly Blackberry Kush cannabis strain tileLeafly Blackberry Kush cannabis strain effects

Find Blackberry Kush Nearby

Blackberry Kush is a heavy THC-dominant strain that wraps the mind in dreamy, blissful euphoria while lifting pain from the body. With the exhale of its sweet, berry flavors, it’s easy to sink into a new mindset—one that isn’t dominated by throbbing aches and pains.

Browse more strains suitable for generalized pain.

Cannabis Strains That Help With Inflammation and Arthritis

Leafly Harlequin cannabis strain tileLeafly Harlequin cannabis strain effects

Find Harlequin Nearby

Looking for cannabis that will quiet the roar of pain without a foggy mind? Try out the high-CBD strain, Harlequin. Its uplifting and clear-headed effects set it apart from heavier, more intoxicating options and make it a perfect choice for daytime medicating.

Leafly Blue Widow cannabis strain tileLeafly Blue Widow cannabis strain effects

Find Blue Widow Nearby

Blue Widow is a prolific hybrid cross between parent strains Blueberry and White Widow. Leafly reviewers praise Blue Widow for its anti-inflammatory qualities, and perhaps the reason for this is Blue Widow’s rich terpene profile that typically boasts high levels of caryophyllene alongside a hearty cannabinoid content.

Browse more strains suitable for inflammation and arthritis.

Try These β-Caryophyllene Cannabis Strains for Pain & Inflammation Relief

Cannabis Strains That Help With Headaches and Migraines

Leafly Purple Arrow cannabis strain tileLeafly Purple Arrow cannabis strain effects

Find Purple Arrow Nearby

Purple Arrow hits the target somewhere between heavy pain relief and uplifting euphoria, making it a great choice for headache sufferers needing swift relief without overly sedating effects.

Leafly Blueberry Headband cannabis strain tileLeafly Blueberry Headband cannabis strain effects

Find Blueberry Headband Nearby

Headband hybrids are commonly described as “cerebral” with effects that go straight to the crown of your head. Blueberry Headband lives up to its name, delivering focused headache relief and a sweet berry flavor.

Browse more strains suitable for headaches and migraines.

Cannabis Strains That Help With Cramps

Leafly Redwood Kush cannabis strain tileLeafly Redwood Kush cannabis strain effects

Find Redwood Kush Nearby

With effects that relax tension in both mind and body, Redwood Kush is known to deliver a woody forest aroma alongside hefty amounts of THC to help ease muscle cramping.

Leafly Dynamite cannabis strain tileLeafly Dynamite cannabis strain effects

Find Dynamite Nearby

Dynamite is another high-THC strain that blows pain and cramping out of the water, but be wary: Dynamite is also known to incite the power of the munchies.

Browse more strains suitable for cramps.

Cannabis Strains That Help With Spinal Injury Pain

Leafly Cataract Kush cannabis strain tileLeafly Cataract Kush cannabis strain effects

Find Cataract Kush Nearby

Cataract Kush is a heavy-hitting hybrid cross between powerhouse classics LA Confidential and OG Kush. This strain’s potency may not be for the novice consumer, but it’s perfect for patients needing a strain that can expertly annihilate pain associated with spinal injury.

Leafly Mazar I Sharif cannabis strain tileLeafly Mazar I Sharif cannabis strain effects

Find Mazar I Sharif Nearby

Descending from some of the earliest landraces of Afghanistan, Mazar I Sharif is a relentless painkiller with a potency you can see on her heavy blanket of crystal trichomes. Afghani strains have a reputation for their high cannabinoid contents, so it isn’t hard to imagine that so many patients have found relief from stubborn pain in Mazar.

Browse more strains suitable for spinal injury.